Manchester City - Chelsea 1:0
Liverpool - Sunderland 2:2
Arsenal - West Bromwich Albion 2:3
Bolton - Manchester United 2:2
Fulham - Everton 0:0
West Ham United - Tottenham 1:0
Blackpool - Blackburn 1:2
Birmingham - Wigan 0:0
Wolverhampton - Aston Villa 1:2
Newcastle United - Stoke City 1:2
Celkem v šestém kole Premier League padlo 24 branek, což je průměrně na zápas 2,4 gólů.
následující kolo:
| Chelsea FC | - | Arsenal F.C. | 3. 10. 2010 |
| Manchester City FC | - | Newcastle United FC | 3. 10. 2010 |
| Birmingham City FC | - | Everton FC | 2. 10. 2010 |
| FC Liverpool | - | Blackpool FC | 2. 10. 2010 |
| Stoke City | - | Blackburn Rovers FC | 2. 10. 2010 |
| Sunderland AFC | - | Manchester United | 2. 10. 2010 |
| Tottenham Hotspur FC | - | FC Aston Villa | 2. 10. 2010 |
| West Bromwich Albion | - | Bolton Wanderers FC | 2. 10. 2010 |
| West Ham United | - | Fulham FC | 2. 10. 2010 |
| Wigan Athletics FC | - | Wolverhampton Wanderers | 2. 10. 2010 |
tabulka po 6. kole:
| Por. | Tým | Z | V | R | P | Skóre | B |
|---|---|---|---|---|---|---|---|
| 1 | Chelsea | 6 | 5 | 0 | 1 | 21:2 | 15 |
| 2 | Manchester Utd. | 6 | 3 | 3 | 0 | 16:9 | 12 |
| 3 | Arsenal | 6 | 3 | 2 | 1 | 16:7 | 11 |
| 4 | Manchester City | 6 | 3 | 2 | 1 | 7:2 | 11 |
| 5 | Aston Villa | 6 | 3 | 1 | 2 | 8:10 | 10 |
| 6 | West Bromwich | 6 | 3 | 1 | 2 | 8:11 | 10 |
| 7 | Fulham | 6 | 1 | 5 | 0 | 7:6 | 8 |
| 8 | Tottenham | 6 | 2 | 2 | 2 | 6:5 | 8 |
| 9 | Blackburn | 6 | 2 | 2 | 2 | 7:7 | 8 |
| 10 | Newcastle | 6 | 2 | 1 | 3 | 9:8 | 7 |
| 11 | Sunderland | 6 | 1 | 4 | 1 | 7:7 | 7 |
| 12 | Bolton | 6 | 1 | 4 | 1 | 9:10 | 7 |
| 13 | Birm'ham | 6 | 1 | 4 | 1 | 7:8 | 7 |
| 14 | Stoke | 6 | 2 | 1 | 3 | 7:9 | 7 |
| 15 | Blackpool | 6 | 2 | 1 | 3 | 9:14 | 7 |
| 16 | Liverpool | 6 | 1 | 3 | 2 | 6:9 | 6 |
| 17 | Wolves | 6 | 1 | 2 | 3 | 7:10 | 5 |
| 18 | Wigan | 6 | 1 | 2 | 3 | 2:13 | 5 |
| 19 | West Ham | 6 | 1 | 1 | 4 | 4:13 | 4 |
| 20 | Everton | 6 | 0 | 3 | 3 | 4:7 | 3 |